Director of Pharmacology
Hybrid / Remote
The Director of Pharmacology will lead the design, execution, and interpretation of in vivo and in vitro pharmacology studies supporting drug discovery and early clinical development programs.
This role will work closely with cross-functional teams across biology, translational science, and clinical development to generate data that informs target validation, candidate selection, and mechanism of action understanding.
Key Responsibilities
- Lead pharmacology strategy across discovery and early development programs
- Design, oversee, and interpret in vivo and in vitro studies to support target validation and translational understanding
- Collaborate with biology, translational, and clinical teams to align preclinical strategy with development goals
- Evaluate pharmacodynamic and pharmacokinetic relationships to support dose selection and mechanism of action
- Oversee external studies conducted with CROs, academic partners, and vendors
- Ensure high-quality data generation, analysis, and reporting across all pharmacology studies
- Contribute to IND-enabling packages and regulatory documentation as needed
- Present data and insights to internal leadership and external stakeholders
- Support identification and advancement of new therapeutic candidates
- Mentor and guide junior scientists and contribute to team development
Qualifications
- PhD in Pharmacology, Biology, or a related life sciences discipline (or equivalent experience)
- 8–12+ years of experience in biotech, pharmaceutical, or CRO environments
- Strong background in in vivo and/or in vitro pharmacology
- Experience supporting early drug discovery and/or translational development programs
- Experience working with CROs and external research partners
- Understanding of PK/PD principles and translational pharmacology
- Experience contributing to IND-enabling studies preferred